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Men's Health · Dual Action

Malegra DXT (Sildenafil + Duloxetine)

Sildenafil 100 mg + Duloxetine 30 mg

In stock

Dual-action oral tablet combining Sildenafil (100 mg) and Duloxetine (30 mg) for erectile dysfunction.

Select pack size:
Total price: $75.00

Prescription notice: this medicine is prescription-only in many countries. Please read our Prescription Policy and speak to your doctor before ordering.

About Malegra DXT (Sildenafil + Duloxetine)

Malegra DXT by Sunrise Remedies pairs sildenafil 100 mg with duloxetine 30 mg — an alternative to dapoxetine-based combos for firmness plus lasting control.

Ships from GMP-certified facilities with batch and expiry printed on every strip, in discreet unbranded packaging.

Consult a healthcare professional before use, especially if you take antidepressants, nitrates or blood-pressure medication. Do not combine with alcohol.

Do not take without medical advice if:
  • Concurrent administration with organic nitrates or nitric oxide donors in any form (severe, potentially fatal systemic hypotension).
  • Co-administration with guanylate cyclase stimulators such as riociguat.
  • Known hypersensitivity to sildenafil or any inactive formulation ingredients.
  • Men for whom sexual activity is inadvisable due to unstable cardiovascular status (e.g., severe heart failure, unstable angina).

How it works

Inhibits cyclic guanosine monophosphate (cGMP)-specific PDE5, enhancing the downstream effects of nitric oxide to relax vascular smooth muscle and augment penile arterial blood inflow during sexual stimulation.

Onset and duration: 30 to 60 minutes prior to anticipated sexual activity; duration of therapeutic effect is approximately 4 to 6 hours.

Possible interactions

  • Nitrates and nitroglycerin preparations (strictly contraindicated).
  • Alpha-adrenergic blockers (risk of symptomatic postural hypotension; initiate with cautious dose spacing).
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir) significantly elevate sildenafil plasma concentrations.
  • Moderate alcohol intake is generally tolerated, but heavy consumption increases vasodilatory adverse effects and impairs erectile response.

Specifications

Active ingredientsSildenafil 100 mg + Duloxetine 30 mg
Dosage formFilm-coated tablets
Pack sizes30, 60 or 120 tablets
Drug classPDE5 inhibitor + SNRI
ManufacturerSunrise Remedies (GMP-certified)
Country of originIndia

Possible side effects

  • Common (>10%): Headache, facial flushing.
  • Frequent (1–10%): Dyspepsia, nasal congestion, visual color tinge (cyanopsia), dizziness.
  • Rare / Serious (<0.1%): Priapism (erections persisting longer than 4 hours requiring urgent emergency intervention), sudden decrease or loss of hearing or vision (NAION).

Official drug information

This information is general and does not replace advice from your doctor or pharmacist.

Frequently asked questions

Malegra DXT (Sildenafil + Duloxetine) contains Sildenafil 100 mg + Duloxetine 30 mg. Phosphodiesterase type 5 (PDE5) inhibitor. Management of adult male erectile dysfunction (ED). Requires sexual arousal to initiate local endogenous nitric oxide release.

Do not take it without medical advice if any of these apply: Concurrent administration with organic nitrates or nitric oxide donors in any form (severe, potentially fatal systemic hypotension). Co-administration with guanylate cyclase stimulators such as riociguat. Known hypersensitivity to sildenafil or any inactive formulation ingredients. Men for whom sexual activity is inadvisable due to unstable cardiovascular status (e.g., severe heart failure, unstable angina).

Orders ship in plain, unbranded packaging. You receive a tracking number within 24 hours of dispatch, and delivery usually takes 7–14 business days depending on destination.

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